Celgene Associate Scientist, Biochemistry in Cambridge, Massachusetts
Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.
The Biochemistry and Molecular Pharmacology Department at Celgene is seeking a highly motivated Senior Associate Scientist to work on the development and execution of cell-based assays. Experience with biochemical assays, cloning and protein expression is a plus. The successful candidate should have a B.S. with at least 6 years’ experience or M.S. degree with at least 4 years relevant experience in biology, molecular biology or a related field.
Responsibilities will include, but are not limited to, the following:• Develop and execute cell-based and biochemical assays to support project teams’ SAR efforts• Construct bacterial and baculovirus expression systems for recombinant proteins • Generate knockout, knockdown or enzymatically inactive target protein cell systems using approaches such as siRNA, shRNA and CRISPR for testing target validation hypotheses• Analyze and report results to the corporate database and project teamsTechnical Skills:• Broadly trained in molecular and cell biology• Demonstrated ability to implement siRNA, shRNA and CRISPR technologies• Experience in designing and carrying out plate-based cell assays • An understanding of basic enzymolology• Ability to independently generate precise, reliable data and skillfully analyze the data is essential • Experience with automated liquid handling systems is a very strong plus • Research experience in inflammatory & autoimmune diseases and/or cancer immunotherapy is a plusOther Attributes:• Ability to function independently within project teams • Ability to reliably execute on team responsibilities in a timely manner • Strong communication and organization skills• Most importantly a positive, problem-solving can-do attitude• ResourcefulGenerally, a high degree of self-motivation fueled by a fundamental interest in contributing to science in general, and drug discovery in particular.
Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.COMMITTED TO IMPROVING THE LIVES OF PATIENTS WORLDWIDE
At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients. Our vision as a company is to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions.
“At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients.”
There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocytic leukemia (CLL), non-Hodgkin’s lymphoma (NHL), triple-negative breast cancer and pancreatic cancer. As committed as we are to clinical accomplishment, we are equally committed to patient support, which is a guiding principle at Celgene. We believe all who can benefit from our discoveries should have the opportunity to do so. Celgene puts patients first with industry-leading programs that provide information, support and access to our innovative therapies.