Celgene Sr. Principal Scientist, Drug Product Development in Cambridge, Massachusetts


Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, ​quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.


The successful candidate will be the key representative for the Drug Product Development group based in Cambridge, Massachusetts. The scientist will provide characterization, preformulation and formulation support to discovery and preclinical groups based in Cambridge.

  • Provides direct on-site pharmaceutical sciences support to enable efficacy, PK, and toxicology studies for Cambridge based discovery groups

  • Provides drug substance physico-chemical characterization & offer solutions to enhance exposure in the preclinical species

  • Provides on-going communication regarding Cambridge Drug Discovery efforts to Pharmaceutical Development and partner groups to ensure organizational awareness, understanding, and alignment.

  • Provides input on development strategy, budgets, timelines, and project development plans

  • May be responsible for technical leadership of junior scientists and contractors.

  • May participate in due diligence assessments and serve as the department’s direct interface with alliance partners

  • Builds and maintains strong working relationship with CRO/CMO partners ensuring that activities are managed collaboratively, efficiently, and effectively


Ph.D. with at least 10 years of work experience, preferred. Bachelor’s degree in a scientific discipline with at least 18 years work experience or Master’s degree with at least 16 years work experience.


  • PhD in Pharmaceutics, Pharmaceutical Science, Pharmaceutical Chemistry, Organic Chemistry or related scientific discipline required

  • 10-year minimum experience in the pharmaceutical industry in small molecule drug discovery and development

  • Demonstrated knowledge, experience, and successful track record in discovery and preclinical support, preclinical formulation development, salt screening and selection, polymorph screening, solid state characterization, and aiding FIH formulation design.

  • Strong fluency in biopharmaceutics

  • Excellent written and verbal communication skills.


Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.COMMITTED TO IMPROVING THE LIVES OF PATIENTS WORLDWIDE

At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients. Our vision as a company is to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions.

“At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients.”

There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocytic leukemia (CLL), non-Hodgkin’s lymphoma (NHL), triple-negative breast cancer and pancreatic cancer. As committed as we are to clinical accomplishment, we are equally committed to patient support, which is a guiding principle at Celgene. We believe all who can benefit from our discoveries should have the opportunity to do so. Celgene puts patients first with industry-leading programs that provide information, support and access to our innovative therapies.