Celgene Scientist, Attribute Science in Warren, New Jersey

Description

Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, ​quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

Scientist, Attribute Science

Principal Bioengineer, Attribute Science

Cell Therapy Development & Operations (CTDO)

Ph.D., M.S., or B.S. in Cell/Molecular Biology, Immunology, Biomedical Engineering, or related discipline

Summary:

The Scientist in Attribute Science group works within Product Science Team, Cell Therapy Development & Operations (CTDO) at Celgene. This position will focus on cell-based assay development to enhance the biological understanding of cellular therapy product pipelines and translate into novel analytical methods/concepts for product and process characterizations and critical quality attributes (CQAs) definition.

The candidate is expected to work independently to develop robust and reliable analytical assays to support characterization of cell products, both from internal pipelines and from external collaborations, from candidate nomination through lifecycle management. The Scientist position is lab-based.

Responsibilities will include, but are not limited to, the following:

  • Design and execute/implement analytical and characterization experiments of high complexity and dimensionality under minimum supervision.

  • Generate and analyze data, report results, present analysis and findings at internal and external group meetings.

  • Work closely with Informatics and Predictive Sciences group to design and execute in vitro studies to advance cell therapy product knowledge and define product attribute candidates.

  • Contribute to the scientific, technical and operational efforts within Attribute/Product Science with regards to product characterization, CQA definition, new assay conceptualization, selection, and method development.

  • Evaluate, improve and implement new protocols when new technology is available.

  • Support critical activities as needed, such as method transfer.

  • Supervise and mentor junior scientists in the development of analytical methods.

  • Interface and collaborate closely with process and analytical development to support CMC development and advance cellular therapy pipelines.

Skills/Knowledge Required:

  • Ph.D. in immunology, cell biology, molecular biology, biomedical engineering, biological science, or related discipline with 3 yrs+ relevant experience, or MS with 5 yrs+ relevant experience, or BS with 8 yrs+ relevant experience in biopharmaceutical development for cell therapies/biologics is required. Expertise and experience in adoptive T cell therapy is preferred.

  • In-depth experience in mammalian cell culture, primary T cell culture, cell counting, flow cytometry, ELISA, and Luminex-based assays.

  • Demonstrated experience in molecular biology techniques, such as DNA/RNA extraction, PCR/qPCR, western blot, molecular cloning, gene knockdown.

  • Experience in the development of cell and immune based test methods.

  • Ability to read, analyze, and interpret scientific journals. Proficiency in Microsoft Office software suite and common statistical analysis software such as GraphPad, JMP, etc.

  • Excellent laboratory and organizational skills.

  • Ability to write scientific technical protocols, reports and SOPs.

  • Excellent verbal and written communication skills and interpersonal skills.

  • High motivation and drive to acquire new skills.

Please visit www.celgene.com to learn more about current opportunities at Celgene. To apply for this position, please visit the career section.

  • Celgene Corporation is an equal opportunity employer.

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.COMMITTED TO IMPROVING THE LIVES OF PATIENTS WORLDWIDE

At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients. Our vision as a company is to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions.

“At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients.”

There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocytic leukemia (CLL), non-Hodgkin’s lymphoma (NHL), triple-negative breast cancer and pancreatic cancer. As committed as we are to clinical accomplishment, we are equally committed to patient support, which is a guiding principle at Celgene. We believe all who can benefit from our discoveries should have the opportunity to do so. Celgene puts patients first with industry-leading programs that provide information, support and access to our innovative therapies.