Celgene Scientist CAR-T Analytical Development in Warren, New Jersey

Description

Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, ​quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries, and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

Scientist CAR-T Analytical DevelopmentWarren, NJ

DEPARTMENT

Cell Therapy Development

PREREQUISITES

B.S. or M.S. in Biology, Immunology Biochemical or Biomedical Engineering or related discipline with relevant experience

Summary:

Independently design, perform and interpret complex experiments to support analytical method development and characterization. Leads and advances analytical projects from Analytical R&D to Quality Operations. Collaborates with analytical development scientists focused on analytical assay qualification and validation, participate in analytical transfers, troubleshoot issues, and support GMP manufacturing activities. Guide analytical team members on strategic direction for method development experiments and communicate with external collaborators.

Responsibilities will include, but are not limited to, the following:

  • Independently design and execute/implement complex cellular analytical development and optimization studies

  • Organize and analyze data, prepare protocols and reports

  • Prioritize scientific and organizational responsibilities

  • Maintain proficiency in analytical skills, statistical analysis, and effective presentation of analysis

  • Solve problems that arise, including those in larger teams and analytical assay transfers

  • Collaborate with statisticians to design experiments and interpret data

  • Present research findings to other groups and provide broader scientific guidance

  • Document experimental results in peer-reviewed reports

  • Transfer analytical methods between internal and external partners

  • Define/maintain a safe work environment in accordance with policies/procedures/regulations

Skills/Knowledge Required:

  • B.S. in Biology, Immunology Biochemical or Biomedical Engineering related discipline with 5 - 8 years of relevant experience or M.S. with 4-9 years of relevant experience

  • Creativity to develop and characterize analytical assays for autologous cell-based therapies

  • Experience in flow cytometry, cell culture, ELISA and functional cellular assays

  • Excellent organization skills and ability to handle multiple tasks

  • Highly motivated, willingness to acquire new skills and ability to work without supervision

  • Strong analytical and scientific knowledge appropriate for cell therapy development

  • Ability to assess risk and develop contingency plans for analytical risks

  • Experience working in a regulated environment and preparing regulatory documents

  • Interpersonal and leadership skills to work with teams in different functions and organizations

#LI-POST

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.COMMITTED TO IMPROVING THE LIVES OF PATIENTS WORLDWIDE

At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients. Our vision as a company is to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions.

“At Celgene, we seek to deliver truly innovative and life-changing drugs for our patients.”

There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocytic leukemia (CLL), non-Hodgkin’s lymphoma (NHL), triple-negative breast cancer and pancreatic cancer. As committed as we are to clinical accomplishment, we are equally committed to patient support, which is a guiding principle at Celgene. We believe all who can benefit from our discoveries should have the opportunity to do so. Celgene puts patients first with industry-leading programs that provide information, support and access to our innovative therapies.